Transplantologiya

Bone marrow transplantation in Israel is a transfer of bone marrow, which contains at least 1% of stem cells (SC), for the treatment of leukemia, lymphomas, aplastic anemia, oncologic and autoimmune diseases. In Israel, at the Hadassah hospital, transplantation is used both in case of disruption of their own stem cells work, and as substitution therapy.

In Israel, at the Hadassah hospital, the bone marrow transplantation department employs the best specialists who are recognized in many countries due to numerous studies on this topic and the effectiveness of innovative developments used in transplantation. Their experimental research continues in treatment of malignant neoplasms, hematological pathologies. The medical center has its own bank of donor stem cells, where the collection, separation and preparation of biological material is carried out.

To get prompt consultation with the Hadassah doctors on your case, fill out the form by attaching the documents:

Prediction

Transplantation is provided when the own tissues are changed and not able to properly fulfil their functions. The procedure allows:

• to replace the pathological hematopoietic system with a healthy one (lymphoma, leukemia, melanoma, myelodysplasia);
• to treat oncology by increasing the body immune status;
• to restore the process of self-destruction of pathological, malignant elements by activation of cytotoxins and reparation;
• to normalize the immune balance, which helps to heal patients with autoimmune, hereditary disorders (thalassemia);
• to improve the reparation of damaged nerve and muscle cells, which helps to increase the prediction of some neurological, neuromuscular pathologies (Alzheimer’s, Parkinson’s).

In Israel, the effectiveness of this procedure for various types of cancer continues to be studied. This is often the only way to prolong the life of patients.

Statistics

The SC transfer procedure requires a compatible donor material and provision of conditions for the patient while the patient is being prepared for the procedure and after it. In Israel there is all the necessary equipment, for example, a sterile conditioning system, which was proposed by researchers of the medical center and is successfully used in many countries.

In Israel, the methods of bone marrow transplantation (from a twin, relative, donor) have been improved and new methods have been developed to minimize the risk of rejection (autologous), the effectiveness of which can be read in the reviews of our patients.

Autologous and syngeneic transplantation shows 100% compatibility; when using material from relatives, the indicator is slightly less. But even with the selection of a donor, patients have a 40% chance of a successful operation, although sometimes they have to wait 3 — 4 weeks.

If you want to learn more about the treatment methods on your case now, fill out the form by attaching the documents:

Methods

If a bone marrow transplantation is required, you can make an appointment on our website. Arriving in Israel, from the first day of visiting the hospital, leading Israeli doctors will deal with you:

1. Professor Reuven Or — Head of the Bone Marrow Transplantation Unit at the Hadassah hospital. He received his medical education at Milan University in Italy, then continued his studies in the USA. Received Ph.D., actively participated in the organization of the Transplantology Department.
2. Dr. Grisaru Sigal — is the director of the Bone Marrow Transplantation Hospital. Received education at the Hebrew University in Israel, continued her studies at the Hadassah hospital. She is an MD, engaged in scientific activities, teaches.

After examination and filling out the medical history, studies will be assigned to confirm or establish an accurate diagnosis. The reports of previous tests will be verified and used if they meet the requirements of the Israeli specialists.

The examination includes:

• various blood tests;
• bone marrow biopsy, performed with anesthesia;
• determination of the patient`s general condition (ECG);
• computed tomography, magnetic resonance imaging, PET-CT if necessary.

All tests are safe and have practically no contraindications.

After receiving the results, a council of doctors determines a treatment plan, which consists of several stages:

1. Donor selection. Autologous material obtained from the patient is used if possible. If it is impossible to take a biomaterial from a patient or it does not meet the necessary indicators, relatives are checked for compatibility or databases are searched.
2. Biomaterial processing. This can be the isolation of individual populations, the cultivation of lymphocytes with tumor antigens, the creation of clones, the activation of T-lymphocytes, which depends on the diagnosis.
3. High-dose therapy for the destruction of abnormal cells in the patient’s bone marrow. It is carried out within 5 — 6 days. It is one of the most difficult periods, in which the health condition rapidly worsens, getting infections is possible. During this time, the patient is in a specially equipped sterile room.
4. Introduction of the prepared graft through a special catheter.
5. Rehabilitation takes 3 — 4 weeks. During this time, immunosuppressants are inserted to improve engraftment.

Effective techniques that are used in Israel for bone marrow transplantation, according to statistics, give good results, so thousands of patients come here for treatment, including from the Russian Federation.

How much does a bone marrow transplantation cost in Israel?

Hadassah has been engaged in research on bone marrow transplantation for many years: due to our innovative developments, the treatment cost in Israel is 20-30% lower than in the USA or Western Europe. Our prices are regulated by the Israeli Ministry of Health, and payment is made to the cashier desk of the hospital without intermediaries.

The cost of a bone marrow transplantation in Israel is influenced by the presence of a close relative of the donor, the general condition of the patient, and the need of preliminary preparation.

You can find out more about the terms and costs by filling out the feedback form by attaching files. As soon as we receive your files, a Russian-speaking employee of the Hadassah international department will contact you and tell you about all the details of your stay in the medical center and the treatment of multiple sclerosis.

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Hadassah University Hospital, Israel

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